Dr. Leverone was the first physician in the Western United States to use ketamine infusions to treat pain, beginning at the beginning of the 21st century. He then became one of the first to use ketamine infusions to treat mental health disorders when these techniques were first described. Dr. Leverone has some of the longest and broadest experience in administration of ketamine, and has been instrumental in the development and refinement of protocols as used in clinics all over the U.S. Dr. Leverone has also served as expert consultant in legal cases involving administration of ketamine, and has helped other practitioners open ketamine clinics in many different states across the U.S.